Magnesium + B6
5-in-1 Magnesium
Key Benefits
Five forms of magnesium. One daily capsule. Everything your body needs magnesium for.
This is for you if you struggle to fall asleep or wake up feeling tired. You feel tense, stressed or overwhelmed. You experience muscle cramps, twitching or restless legs. You already take vitamin D and want it to actually work. You've tried single-form magnesium supplements and seen little difference.
Most magnesium supplements contain a single form. The problem is that different forms of magnesium are absorbed differently and work in different parts of the body. Our 5-in-1 magnesium complex combines the five most clinically relevant forms, which are then activated by B6. Ensuring nothing is missed, restoring your whole-body magnesium.
- Magnesium Glycinate: Deeper, more restorative sleep.
- Magnesium Citrate: Gut motility
- Magnesium Malate: Malic acid to move magnesium deeper into the muscle and tissue
- Magnesium Marine: Slow-release magnesium with trace minerals
- Magnesium Oxide: High-strength magnesium, delayed release for brain support
- Vitamin B6: Increases absorption and activation
Magnesium has been linked to supporting symptoms of stress and anxiety by regulating cortisol and optimising GABA (the brain’s natural calming signal). Magnesium is required for over 300+ enzymatic reactions that help support and regulate our immune system. And this is why it is the perfect pair with our VitamoreD to support activation and conversion of vitamin D3 in the kidneys.
How It Works
Why there are five forms of magnesium in our formula and what each form actually does.
Magnesium is the fourth most important mineral in the human body and is involved in over 300 biochemical reactions. For example, it supports nerve conduction, the process by which our nervous system transmits signals. We need magnesium, but not all magnesium compounds reach the same tissues. Each form of magnesium has a different absorption route and a different function. That's why one form of magnesium is never enough to replenish whole-body magnesium.
That’s why our nutritionist and founder, Tracey, formulated Daily Magnesium with more than just glycinate: in clinical practice, she saw that multiple forms of magnesium are needed to truly restore levels across the whole network, because different forms prioritise different areas.
Magnesium Glycinate: A form where magnesium is bound to the amino acid glycine, which our bodies naturally create; glycine has been shown to help regulate the nervous system and support serotonin production, which helps regulate mood, sleep, digestion, and learning.
Magnesium Citrate: A magnesium form bound to citric acid, because of citrate's high solubility, can blend well with water, breaking down quickly, allowing it to deliver magnesium into the digestive tract, supporting not only rapid absorption of the magnesium but also helping to support regulation of digestion, especially for people who experience slow gut motility or who are prone to constipation. A go-to for people who are magnesium-deficient and need a fast boost in magnesium levels.
Magnesium Malate: Bound to malic acid, a key compound our body produces and the key acid that makes up 90% of apples! Malic acid is a key component of our Krebs cycle. This is a key metabolic process which takes place in the mitochondria of your cells. This is where carbohydrates, proteins, and fats are broken down to generate adenosine triphosphate (ATP), the primary energy source fueling your body. This is why this key form of magnesium is used to move it deeper into the muscle and tissue, and also why it is one of the preferred forms used by athletes and people with chronic fatigue, as it provides sustained energy, reduces fatigue and supports muscle recovery.
Magnesium Marine: A game-changing natural magnesium, extracted from the Atlantic seawater of the Irish coast. This isn’t just normal magnesium; Aquamin (marine magnesium) contains 70+ trace minerals, which help it cross the intestinal epithelium and increase magnesium absorption. Read the research.
Magnesium Oxide: A high-strength magnesium source, with over 60% of the compound being elemental magnesium. This is one of the most misunderstood forms of magnesium because, when attached to oxygen, it can release magnesium more slowly, allowing it to deliver magnesium to the brain and support cognitive function and sustained replenishment. It has gained a bad reputation due to its high elemental magnesium content (60%) compared to glycine (13%), which has led to digestive discomfort and diarrhoea. That's why, in our formulation, we use the optimal amount to provide the benefits without the discomfort.
+ Vitamin B6: This methylated B vitamin was added to our formulation because B6 supports the cellular uptake of magnesium, enhancing magnesium's effectiveness within the cells. In one study, magnesium + B6 improved the production of Serotonin and GABA, which in turn improved participants' sleep, mood, and stress. Read the research.
Ingredients
We don’t hide our magnesium forms. We don’t hide our elemental magnesium. You won’t find any buffered or hidden magnesium here. Read more about buffered magnesium.
Multi-Source 5 in 1 Magnesium Complex (Per 2 Capsules)
- Aquamin® Marine Magnesium - 400mg
- Magnesium Citrate - 316mg
- Real Magnesium Glycinate - 350mg
- Magnesium Malate – 300mg
- Magnesium Oxide – 180mg
- Total Magnesium - 1546mg
- Total Elemental Magnesium: 375mg
- Vitamin B6 (Pyridoxal-5-Phosphate): 2mg
Read Our Label
Other ingredients: hydroxypropyl methylcellulose (capsule shell) and bamboo extract
The Science
The science behind our Daily 5-in-1 Magnesium with B6
Magnesium deficiency is common, and most supplements won’t fix it.
Modern farming, food processing, stress, alcohol, and certain medications all deplete magnesium faster than our modern diets can replenish. In UK soil, according to reports produced independently by Natural Resource Management, there is 40% less magnesium than 60 years ago.
Furthermore, a standard blood test doesn't reliably detect deficiency; only 1% of the body's magnesium is in the bloodstream, so serum levels can appear normal until deficiency is severe, as 99% of magnesium is stored in the bones, cells, and muscles.
Why different forms of magnesium matter
Each form of magnesium has a carrier; this is where magnesium is attached to another molecule. For example, in magnesium bisglycinate, the amino acid glycine carries the magnesium. In magnesium citrate, citric acid carries the magnesium. Because of the magnesium carrier, magnesium can be distributed to different areas of the body. For example, the amino acid glycine can distribute magnesium to the central nervous system, connective tissue, and skin.
So, different forms of magnesium reach different tissues. One form of magnesium can not do the job of five, and without B6, magnesium’s activation is slower. This is why it’s important to be taking a multiform, 5-in-1 magnesium supplement.
Studies show that the body's absorption and use of magnesium depend largely on the type of magnesium. Magnesium glycinate is known to cross the blood-brain barrier via glycine transporters and is well tolerated, so it is often used in research on sleep and anxiety. Magnesium malate is taken up mainly by muscles and supports the Krebs cycle; research suggests it may reduce muscle fatigue and pain. Magnesium citrate dissolves well in the digestive tract and is used to support gut motility and overall magnesium absorption. Aquamin marine magnesium comes from Atlantic seawater and contains magnesium plus over 70 natural trace minerals, which help with absorption and activity in ways that synthetic salts cannot match. Magnesium oxide releases much more slowly than other forms of magnesium. The delayed release allows magnesium to travel further through the digestive tract, helping replenish magnesium levels throughout the body, and, in studies, has been shown to be a beneficial form for supporting brain function, especially in conditions such as migraine.
Why we use 5 forms of magnesium in our supplement
We chose not to make a daily magnesium supplement with only glycinate because that would mainly help with sleep and easing anxiety, but magnesium does much more. Using just magnesium glycinate would not support other important areas like energy, heart health, and muscle function, and it would miss out on marine minerals that help your body absorb magnesium. That’s why our daily 5-in-1 magnesium supplement combines several forms of magnesium in one capsule to restore your whole body's magnesium.
Why we add B6 to our magnesium supplement
When we designed our daily magnesium supplement, we focused not just on the magnesium form but also on what would help increase absorption and activation. The 2018 Pouteau et al. randomised clinical trial was the first study to directly compare magnesium alone versus magnesium combined with vitamin B6 (pyridoxine) in adults with stress and low serum magnesium. Research shows that vitamin B6 helps magnesium enter cells by acting as a cofactor. If there is not enough B6, less magnesium is absorbed by cells, and more is lost through the kidneys.
The results showed that the group taking both magnesium and B6 had about 24% greater stress reduction than the control group taking only magnesium, especially in people who were severely stressed. After 8 weeks, the combination group saw stress levels drop by nearly 50% from their starting point. A 2021 follow-up analysis of the same trial also found that the combination led to bigger improvements in anxiety, depression, and quality of life
Why does this matter for our daily magnesium?
Most magnesium supplements do not include B6. Adding Vitamin B6 (pyridoxine), as we do in our magnesium, is supported by clinical trial evidence showing it improves outcomes by activating magnesium for stress, sleep, and mood, as shown in the study by Pouteau et al. Especially for people who do not get enough B6 through diet alone. So, choosing a magnesium supplement without B6 means missing out on proven benefits.
How To Use
Take 1 capsule twice daily.
- We recommend taking 1 capsule with your lunch and 1 capsule with your evening meal. However, you can also take 2 capsules together with either meal instead of splitting the dosage.
- We recommend taking your magnesium with food. Our magnesium formulation is gentle on the stomach, but taking it with food may help support absorption of the magnesium.
- Take magnesium daily for at least 2 to 4 weeks to feel the full effects. Most of our customers have reported seeing a difference within the first week in their sleep, energy and overall stress.
Important note:
- Do not exceed the recommended dosage of 2 capsules daily. The recommended daily amount (RDA) of magnesium is 375 mg, which our Daily Magnesium meets.
- If you are on any blood pressure medication, diabetes medication, or antibiotics, speak to your GP before use.
Pair with VitamoreD for the full benefit
Magnesium activates vitamin D. Take together for immune support, bone health, and mood. Especially important from October to March in the UK.
Frequently bought with:
5-in-1 Magnesium
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