The Hay Fever Bundle

The Hay Fever Bundle is our Daily pre-season routine for people who get hay fever every year. Toxaprevent medical-grade zeolite (Purple sachets and Red capsules) binds histamine (released in response to pollen and other irritants that create symptoms associated with allergies) and other irritants in the gut, so less is absorbed. VitamoreD (10 µg vitamin D3 as calcifediol) and the 5-in-1 Magnesium Complex + B6 support normal immune and nervous system function. Vitamin D and vitamin B6 contribute to the normal function of the immune system. This bundle is designed to work alongside antihistamines and nasal sprays, and is best started 6 weeks before your pollen season.

Hay fever is an allergic reaction to pollen. When pollen enters your nose, mouth, and eyes, immune cells called mast cells release histamine. Histamine creates an inflammatory barrier (blocking) more pollen from entering, creating symptoms such as runny eyes (washing the pollen away), sneezing (pushing the pollen out of the respiratory channels) and a blocked or runny nose (blocking the pollen from entering the respiratory system and pushing it out through the runny nose).

Antihistamines block histamine's effects after it's released from mast cells. Antihistamines block histamine from reaching specific histamine receptors; in pollen allergies, the H1 receptor (located in the skin, where your body first interacts with pollen). The daily hayfever bundle works differently. Toxaprevent binds and removes histamine and other irritants from your gut, while vitamin D and magnesium work together to replenish nutrients your immune system relies on:

• Lighten the histamine load: Toxaprevent contains zeolite clinoptilolite, which binds and removes excess histamine. So, you start the allergy season with less histamine, freeing up your body's natural DAO and HNMT.
• Immune system support: Vitamin D and vitamin B6 contribute to the normal function of the immune system. VitamoreD's calcifediol form raises vitamin D levels faster than standard D3.
• Less tiredness and fatigue: Pollen season often brings poor sleep and low energy. Magnesium and vitamin B6 contribute to the reduction of tiredness and fatigue.
• Pre-season, timed for spring: Designed to be taken before allergy season starts in March. Starting early helps reduce the backlog of histamine and supports vitamin D levels, which contribute to the normal function of the immune system.
• Works alongside antihistamine: The protocol isn't designed to block histamine receptors like an antihistamine; it reduces the histamine load. You can continue using your antihistamine, eye drops, or steroid nasal spray; just leave a two-hour gap: take the medication first, then Toxaprevent 2 hours later.

Hay fever or histamine intolerance?

If your symptoms only flare in pollen season, this bundle is designed for you. If you react to food all year round, with headaches, flushing, gut symptoms or hives, look at our Histamine Protocol instead.

Clear: The histamine bucket.

Think of your histamine body as a ‘bucket’. Pollen pours in; your immune system releases histamine during allergy season. However, other things can trigger histamine release, including histamine-rich foods (e.g., cheese, wine, cured meats), gut bacteria (caused by dysbiosis), stress, and even environmental pollutants, which keep adding to it all year.

When the ‘bucket’ overflows, symptoms appear, as histamine travels and attaches to different histamine receptors. You can't stop the pollen, but you can work on how full the histamine bucket is before the season starts. Research on Toxaprevent showed that it can bind histamine and remove it from the body through the stool, helping empty the histamine bucket by supporting the natural DAO and HNMT enzymes responsible for breaking down biogenic amines.

How Toxaprevent works.

Think of Toxaprevent as a negatively charged magnetic garbage truck designed to remove the heavy metals, which in this scenario are positively charged rubbish.

1. Travel: Toxaprevent Sachets travel through and work in the Upper GI, and Toxaprevent Capsules travel deeper into the Lower GI. The 'garbage trucks' travel to specific areas of the gut, picking up toxins.
2. Bind & Hold: Toxaprevent's active ingredient MANC® pulls or collects the heavy metals and holds them in the 'garbage truck'. Once Toxaprevent has bound to these toxins, they can not be re-released.
3. Remove: Toxaprevent, with the heavy metals, leaves the body through the stool. This stops the heavy metals from being reabsorbed.

Taking Toxaprevent daily reduces the heavy metal burden from the body. We recommend taking both Toxaprevent products daily for three months, then choosing either the sachets or the capsules and continuing for three months.

Restore & Balance: Immune and nervous system balance

Vitamin D is a prohormone. Whether it comes from sunlight or a traditional D3 (cholecalciferol) supplement, your body must convert it twice before your cells can use it, and both conversions rely on magnesium-dependent enzymes.

How Vitamin D and Magnesium Work Together in 3 steps

Step 1

• Standard D3 (Cholecalciferol or Sunlight)
• Transported via blood into the liver. Uses and needs magnesium to convert.
• Liver converts D3 into 25(OH)D3 (a.k.a Calcifediol = VitamoreD)

Step 2

• VitamoreD = Calcifediol 25(OH)D - The circulating form your blood test measures. And where VitamoreD starts.
• Kidneys convert Calcifediol into Calcitriol (1,25-Dihydroxyvitamin D), the active hormone form of vitamin D. Uses and needs magnesium to convert.

Step 3

• Calcifediol circulates through the blood bound to protein; 99% of Calcifediol is attached to the protein.
• Calcifediol travels and attaches to vitamin D receptors (VDR), delivering all the health benefits that come with hormonal D3.

VitamoreD

VitamoreD is Calcifediol, meaning it requires no liver conversion. It is absorbed more efficiently than traditional cholecalciferol D3 and D2, which require fat for absorption and can also get stored in fat tissue, unlike calcifediol, which is hydrophilic and doesn't require fat for conversion. That is why studies show that calcifediol increases vitamin D levels faster and more predictably than cholecalciferol.

5 in 1 Daily Magnesium + B6

Magnesium is a cofactor for the enzymes that convert vitamin D and helps regulate how much vitamin D is activated or broken down. Five forms (glycinate, citrate, malate, oxide and Aquamin® marine magnesium) absorb at different rates, giving a steadier supply than a single form. The Daily formula includes vitamin B6 as active P-5-P because research suggests B6 helps magnesium cross the cell membrane and increases bioavailability and uptake.

Why take both Toxaprevent Capsules and Sachets?

Each Toxaprevent is designed to work in a specific area of the digestive tract. The Sachets work in the Upper digestive tract, the mouth and stomach, binding irritants right away; the capsules work lower down and deeper in the digestive system. Think about this: your digestive system is 30 feet (9 meters) long. That’s a lot of space to cover, so each product is designed to cover as much of the digestive system as possible. That is why it's important to use both products together daily so they can help reduce the daily irritant burden. Both Toxaprevent products cover the entire digestive tract.

What's in the hayfever bundle:

• 1 x Toxaprevent Medi Plus Sachets (Targets Upper GI: Mouth, Oesophagus and Stomach) | 30 Sachets = 30-Day Supply (1 sachet daily)
• 1 x Toxaprevent Medi Pure Capsules (Targets Lower GI: Intestines and Colon) | 180 Capsules = 30-Day Supply (6 capsules daily)
• 1 x VitamoreD Tablets (Immune support) | 60 tablets = 60 days supply (1 tablet daily)
• 1 x Daily 5 in 1 Magnesium | 60 Capsules = 30 days supply = (2 capsules daily)

Toxaprevent product ingredients:

• 1 x Toxaprevent Medi Plus Sachet contains 2400mg of MANC® particles (Modified Activated Natural Clinoptilolite) blended with 420mg calcium carbonate and 180mg magnesium carbonate.
• 1 x Toxaprevent Medi Pure Capsule contains 400mg of MANC® (Modified Activated Natural Clinoptilolite), Capsule shell: Cellulose, and Gellan Gum.

Per 1 easy-swallow VitamoreD tablet:

• 10 mcg (1000 I.U.) Dyna-Cal 25-OH Vitamin D3 (Calcifediol).

Natural Ingredients: Cellulose, Magnesium salt of fatty acids (sourced from sustainable palm oil).
Gut-Friendly Coating: Hydroxypropylmethyl Cellulose (HPMC) and Ethyl Citrate for stability, integrity and improved absorption.

Multi-Source 5-in-1 Magnesium Complex (Per 2 Capsules)

• Aquamin® Marine Magnesium - 400mg
• Magnesium Citrate - 316mg
• Real Magnesium Glycinate - 350mg
• Magnesium Malate – 300mg
• Magnesium Oxide – 180mg
• Total Magnesium - 1546mg
• Total Elemental Magnesium: 375mg
• Vitamin B6 (Pyridoxal-5-Phosphate): 2mg

Read Our Label
Other ingredients: hydroxypropyl methylcellulose (capsule shell) and bamboo extract

The histamine bucket,

Think of your histamine body as a ‘bucket’. Pollen pours in; your immune system releases histamine during allergy season. However, other things can trigger histamine release, including histamine-rich foods (e.g., cheese, wine, cured meats), gut bacteria (caused by dysbiosis), stress, and even environmental pollutants, which keep adding to it all year.

When the ‘bucket’ overflows, symptoms appear, as histamine travels and attaches to different histamine receptors. You can't stop the pollen, but you can work on how full the histamine bucket is before the season starts. Research on Toxaprevent showed that it can bind histamine and remove it from the body through the stool, helping empty the histamine bucket by supporting the natural DAO and HNMT enzymes responsible for breaking down biogenic amines.

What is MANC® in Toxaprevent?

MANC® stands for Modified Activated Natural Clinoptilolite. Clinoptilolite is a zeolite: a volcanic mineral formed when ash meets water, with a honeycomb structure full of channels. The structure carries a negative charge, which is why it attracts and holds positively charged compounds. Think of a magnet with south and north poles; the north attracts the south, and vice versa.

Raw zeolite varies enormously in purity and particle size. MANC® is purified, activated and milled to a controlled particle size (6 to 10 microns), works only in the gut and is not absorbed. It passes through the digestive tract, does its physical job and is not metabolised or broken down.

Toxaprevent and its active ingredient MANC® bind histamine, heavy metals and ammonium alongside other biogenic amines and remove them from the body through the stool. It's important to note that once Toxaprevent has attached to histamine, it can not be unbound.

Why Toxaprevent is a medical device and not a food supplement

A food supplement is something that fixes a nutritional deficiency by adding key minerals or nutrients we are missing out on. However, Zeolites do not do this. They remove toxins from the body, but not all Zeolites are made the same.

Toxaprevent is classified as a class 2b medical device, and it has held this certification since 2006 because of its safety and quality standards. Toxaprevent is made under an independently audited medical-device quality system (ISO 13485 and 9001); it has a defined intended purpose, and the instructions for use in every box set out exactly how to take it. Its intended purpose is to strengthen the stomach and intestinal wall barrier under recurring strain, and it is particularly suited to situations where levels of ammonium, histamine or heavy metals such as lead and mercury are raised.

Scientific references:

1. Zeolite binds histamine: Selvam T, Schwieger W, Dathe W. Natural Cuban zeolites for medical use and their histamine binding capacity. Clay Minerals. 2014;49:501–512. See also Selvam et al., Environ Geochem Health, 2018: read the study.
2. Vitamin D and allergic rhinitis: Kawada, K.; Sato, C.; Ishida, T.; Nagao, Y.; Yamamoto, T.; Jobu, K.; Hamada, Y.; Izawa Ishizawa, Y.; Ishizawa, K.; Abe, S. Vitamin D Supplementation and Allergic Rhinitis: A Systematic Review and Meta-Analysis. Medicina 2025, 61, 355. Read the study.

How to use VitamoreD and Magnesium Together

Morning: Take 1 VitamoreD tablet and 1 daily magnesium capsule with your morning meal.

Evening: Take 1 daily magnesium capsule with your evening meal.

How long to take:

Take 1 VitamoreD tablet (10 µg) and 2 magnesium capsules daily. Don't exceed this unless a healthcare professional has advised you to. As 10 micrograms is the max daily dosage (UK) and 375 mg is the RDA for magnesium.

USA customers, please note: You can take 2 tablets (20 micrograms) of VitamoreD daily.

Important information:

• Don't double up on vitamin D: if you already take a multivitamin or another vitamin D product, check your total D3 intake with your
• Spacing from medication: keep magnesium about 2 hours away from tetracycline or quinolone antibiotics, thyroid medication and bisphosphonates, as magnesium can reduce their absorption.
• How long: take it daily from autumn to spring at a minimum, or all year if you get little sun.
• Track your vitamin D levels: we recommend tracking your vitamin D levels every 8 to 12 weeks to show you exactly what has changed and how your levels are progressing.

Speak with your healthcare professional if you are pregnant or breastfeeding, are under 18, have kidney disease, high blood calcium, sarcoidosis or another condition that affects calcium or vitamin D metabolism, or take thiazide diuretics, digoxin or other prescribed medication.

Store in a cool, dry place away from direct sunlight.